Antihistaminic agents play a crucial role in combating allergic reactions by inhibiting the action of histamine at its receptors, which are distributed throughout the human body. These agents are classified primarily into H1-antagonists, such as Diphenhydramine hydrochloride and Promethazine hydrochloride, and H2-antagonists, like Cimetidine and Ranitidine. Gastric proton pump inhibitors, including Omeprazole and Pantoprazole, also serve to reduce gastric acid