Clinical Pharmacokinetics and Therapeutic Drug Monitoring is a clear and practical guide for Pharm D students, clinical pharmacists, and healthcare practitioners who want to master the science behind individualized dosing. This book translates complex pharmacokinetic and pharmacodynamic principles into real world clinical decision making so readers learn how to adjust therapy with confidence and precision.
Across twenty three structured chapters the book explains how absorption, distribution, metabolism, and excretion shape drug exposure and how these processes guide the design of effective dosage regimens. It examines the impact of renal and hepatic disease, genetic variation, special populations, and drug interactions on dosing decisions. Readers also gain a comprehensive understanding of therapeutic drug monitoring including sampling strategies, interpretation of drug levels, and protocols that support safe and effective therapy.
The text presents population pharmacokinetics, Bayesian forecasting, and model informed precision dosing in a simple and clinically relevant manner. Each topic is supported by practical examples that highlight real clinical challenges such as managing antiepileptics, antibiotics, immunosuppressants, and drugs with narrow therapeutic ranges.
Written by experienced academicians, this book serves as both a teaching resource and a point of care reference.
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Dr. Parimala, Dr. Bhavani, Dr. Krupa Rani
Dr. Parimala Birudula, Pharm.D (Ph.D), serves as an Assistant Professor at Chennupati Indo-American School of Pharmacy, Jonnalagadda. Her expertise spans Pharmacotherapeutics, Clinical Pharmacy, and Medication Safety. She has contributed to the well-regarded Pharmacotherapeutics-II textbook and authored several scientific papers. Her teaching style focuses on clear clinical reasoning and patient-centered thinking, which makes complex therapeutic concepts easy for learners. Her academic and clinical strengths position her as a credible guide for readers seeking accurate and practical insights into modern pharmacotherapy.
Dr. Katta Bhavani, Pharm.D, is an Assistant Professor at Chennupati Indo-American School of Pharmacy with a strong focus on hospital-based clinical training. She specializes in Pharmacotherapeutics and Clinical Pharmacy Practice and is known for her disciplined, student-focused approach. She trains Pharm.D students through ward rounds, case discussions, and clinical documentation, helping them build real-world therapeutic skills. Her active presence in hospital settings ensures students learn through direct patient-care exposure. This hands-on experience enhances her credibility as an educator who understands how pharmacotherapy works at the bedside.
Dr. P. Krupa, Pharm.D, is an Assistant Professor in the Department of Pharmacy Practice at QIS College of Pharmacy, Ongole. Her interests include Pharmacovigilance, clinical research, and evidence-based Pharmacotherapeutics. She has authored multiple research papers and leads ongoing studies on drug safety and treatment outcomes. Her mentorship emphasizes critical thinking, medication-error prevention, and patient safety. With her research and practical teaching experience, she brings an informed and analytical perspective that supports readers looking for trustworthy, evidence-driven information.
