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TEXT BOOK OF PHARMACEUTICAL FORMULATION DEVELOPMENT

Author Name: Dr. Anil Pareek, Prof. (Dr.) Rajesh Kumar Nema, Dr. Vishal Kumar Saxena, Yogesh Kumar Rathore, Dr. Gaurav Singh Sikatwar | Format: Paperback | Genre : Educational & Professional | Other Details

Preformulation studies encompass a range of crucial investigations, including molecular optimization of APIs, analysis of crystal morphology, and assessment of powder flow. These studies delve into structure modification and evaluate drug-excipient compatibility to lay the groundwork for successful formulation development. Methods of determination are meticulously employed to understand the physicochemical properties of drug substances. In parallel, formulation additives are scrutinized, considering factors influencing their incorporation and the evolving landscape of excipient science. This involves leveraging design of experiments like factorial design for comprehensive product and process development. Solubility studies play a pivotal role, with emphasis on experimental determination and techniques such as cosolvency and solid dispersion to enhance drug solubility. Dissolution theories and mechanisms, along with in-vitro dissolution testing models, are explored to elucidate factors influencing dissolution and establish in-vitro and in-vivo correlations. Product stability studies encompass degradation kinetics, stability testing, and interpretation of kinetic data, adhering to stringent protocols and ICH guidelines to ensure pharmaceutical quality and safety.

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Dr. Anil Pareek, Prof. (Dr.) Rajesh Kumar Nema, Dr. Vishal Kumar Saxena, Yogesh Kumar Rathore, Dr. Gaurav Singh Sikatwar

Dr. Anil Pareek has completed B. Pharm. from L. M. College of Science and Technology, Jodhpur (Raj.) in 2002, M. Pharm. from J.S.S. College of Pharmacy, Ooty (TN) in 2007 and PhD from R.U.H.S., Jaipur (Raj.) in 2014. He has been working at L. M. College of Science and Technology, Jodhpur (Raj.) since 2007, currently associate professor in the department of pharmaceutics and taught various subjects in the department at UG and PG level.
Dr. Pareek has guided 13 M. Pharm. (Pharmaceutics) students, has received research project grants from UGC and has published over 20 peer reviewed research/review papers in national and international journals. He is also a reviewer for many journals and a life time member of APTI and LAPA alumni association. He has continued to maintain active research on free radical biology and natural antioxidants.

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