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Synthetic Methods of Indole Derivatives Named Reactions used in the synthesis of Indole Derivatives

Author Name: Kuldeep Singh | Format: Paperback | Genre : Reference & Study Guides | Other Details

Indole is the foremost heterocyclic compound in the entire heterocyclic system. Some of the ring heterocyclics are formed when the benzene ring is fused to five or six-membered heterocyclic compounds at the second and third positions of the benzene ring. It may include indole, benzofuran, quinoline, isoquinoline. Indole plays an integral role in chemical, biological and pharmacological activities. Indole nuclei carry immense importance as it built proteins in the form of amino acid tryptophan and depicts the Skelton of indole alkaloids. Indole binds with high affinity with the multiple receptors. Due to its huge medical importance such as antimicrobial, antiproliferative, antiviral, antifungal, antioxidant, antidiabetic, antihistamine, anti-inflammatory, analgesic, anticancer, antitubercular, antihypertensive, antimalarial, anticholinesterase and many more indole is found to be invariably crucial to study. The medical importance of indole amuses researchers to synthesize diverse types of indole derivatives as it also flair some new therapeutic effects. Indole moiety is a subpart of radical scavengers are found commonly in the body. Indole not only has biological importance but also acquires so many industrial applications say dyes, flavor enhancers, agriculture etc. It also has a significant role in commodity markets. 

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Kuldeep Singh

Dr. Kuldeep Singh, MRSC 
Dr. Kuldeep Singh is an associate professor at Maharishi Markandeshwar (Deemed to be University), Mullana, India. He obtained his Ph.D. in 2007 (IIT Bombay) and continued his postdoctoral research (University of Strasbourg, France). His research activities focus on (a) developing new synthetic methodologies, (b) Application of chemistry principles to better procedures by following green chemistry. He is a member of the Chemical Research Society of India, the Royal Society of Chemistry, the Indian Science Congress Association, the Association of Chemistry Teachers, and the Green Chemistry Network.

Dr. Raman Singh
Dr. Raman Singh joined MMDU, Mullana as an assistant professor in 2014. Before joining MMDU, she worked at National Dope Testing Laboratory, New Delhi. She had completed her doctoral research in organic chemistry from Jiwaji University Gwalior in 2007. Her area of research interest includes antimicrobial resistance, green synthesis, heterocyclic chemistry. She is a member of the Indian Science Congress Association, Association of Chemistry Teachers, Graduate Women in Science, USA, and Green Chemistry Network.

Ms. Lipika Nagpal
Ms. Lipika did her MSc from Maharishi Markandeshwar (Deemed to be University), Mullana, India. Currently she is pursuing her PhD in Heterocyclic chemistry.