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Introduction to Crucial Pharmacology Trends (CPT), Volume 5
Editors: Dr. Shiva Murthy N, Dr. Melvin George, Dr. Phulen Sarma, Dr. Mukundam Borah, and Dr. Bikash Medhi, CPT (Vol. 5) continues the series’ objective of providing a concise, concept-oriented, and examination-focused resource for PGs in pharmacology and young researchers. This volume integrates core pharmacological principles with emerging scientific, clinical, and technological advances shaping modern therapeutics.
Section I: Molecular and Mechanistic Frontiers in Pharmacology explores the molecular basis of drug action, revisiting pharmacodynamic/kinetic concepts such as receptor and non-receptor mechanisms, cytochrome P450 enzymes, cytokine receptors, nuclear receptors, and topics such as sanctuary compartments, vectorial transport, neuropeptides in the gut–brain axis, therapeutic enzymes, and drugs targeting apoptosis and angiogenesis.
Section II: Translational and Experimental Pharmacology connects laboratory research with clinical practice, addressing CRFs design, PK compartment models, drug-induced toxicity, IDDSs, and modern clinical trial approaches.
Section III: Clinical, Ethical, and Emerging Trends in Pharmacology discusses rational prescribing, antimicrobial stewardship, pharmacotherapy in organ failure, drug price regulation, AI in drug discovery, ethical AI frameworks, and therapeutic challenges related to rare diseases and orphan drugs.
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Prof. Shiva Murthy N
Prof. Shiva Murthy N, MBBS, MD, MBA
Professor and Head, Department of Pharmacology, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Bangalore, Karnataka, India.
He is an academic leader with extensive experience in medical education, research, and postgraduate training. His work focuses on advancing clinical pharmacology, academic innovation, and strengthening evidence-based medical practice.
Prof. Melvin George, MBBS, MD, DM
Professor and Head, Department of Clinical Pharmacology, SRM Medical College and Hospital, Chennai, Tamil Nadu, India.
A specialist in clinical pharmacology, he contributes significantly to clinical research methodology, drug development, and therapeutic optimization. His expertise supports the integration of modern research into clinical practice.
Dr. Phulen Sarma, MBBS, MD, DM
Assistant Professor, Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Guwahati, Assam, India.
He is actively involved in academic pharmacology and specialized clinical pharmacology training, contributing to research advancements and postgraduate education.
Dr. Mukundam Borah, MBBS, MD
Assistant Professor, Department of Pharmacology, Gauhati Medical College, Assam, India.
His academic and research interests include foundational and applied pharmacology, promoting scientific learning and research excellence in undergraduate and postgraduate medical training.
Prof. Bikash Medhi, MBBS, MD (AIIMS), MAMS, FIMSA
Professor, Department of Pharmacology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
A recognized academician and researcher, he has contributed extensively to experimental and clinical pharmacology. His work is well regarded for advancing therapeutic research and postgraduate scientific training.
