"It was a wonderful experience interacting with you and appreciate the way you have planned and executed the whole publication process within the agreed timelines.”
Subrat SaurabhAuthor of Kuch Woh Pal
The extracellular matrix (ECM) is a three-dimensional meshwork of proteins, proteoglycans and polysaccharides imparting structure and mechanical stability tissues. A network of high quality protein-protein interactions constructed from these core genes reveals the ECM is organised into biologically relevant functional modules whose components exhibit a mosaic of expression and conservation patterns.ECM dysfunction has been implicated in a number of debilitating conditions including cancer, atherosclerosis, asthma, fibrosis and arthritis. Identifying the components that comprise the ECM and understanding how they are organised within the matrix is key to uncovering its role in health and disease.
This review defines role of Matrix Metalloproteinase -3 and Matrix Metalloproteinase -21 in cancer, also rigorous protocol for Extracellular matrix’s components, functions, merits, demerits and various biological activities.
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Dr. Sivaramakrishnan Muthanandam, Dr.Adhithya B, Dr.Vezhavendhan N
Dr. Sivaramakrishnan Muthanandam, obtained his BDS degree form Rajah MuthiahDentalCollge& Hospital, Annamalai University, Chidambaram in 2009 and his MDS degree from MeenakshiAmmalDental College, MAHER, Chennai in 2013. He is currently working as Associate Professor, Department of Oral & Maxillofacial Pathology and Oral Microbiology, Indira Gandhi Institute of Dental Sciences, Pondicherry. He has been into academics and has been teaching both UG & PG students for 10 years. He has more than 30 international & national publications in indexed journals to his credit. He also has a published online course in VidyaMitra, Inflibnet initiative, under NME-ICET, MHRD, Gov. of India. He has authored a chapter in a book titled: Preterm birth – Prevalence, risk factors & Management. He is also serving in editorial board and peer review team of reputed journals. He is the primary investigator of a project on prevention of oral cancer among Narikuravar tribal population funded by Indian Council of Medical Research (ICMR), Government of India.
Dr Vezhavendhan completed his under graduation and post-graduation in the department of Oral Pathology & Microbiology from Mahatma Gandhi Postgraduate Institute. currently working as professor in the Department of Oral and Maxillofacial Pathology and Microbiology. His area of interest is precancerous disorders of oral cavity. He have published around 40 research work in national and international journals. He is currently involved in projects which help to prevent the transformation of precancerous disorders to cancer.
