This book on Medicinal Chemistry provides a comprehensive exploration of the field, covering the history and development of medicinal chemistry and the importance of physicochemical properties such as ionization and solubility in drug action. It delves into the metabolism of drugs, categorizing them by phase reactions, and presents an in-depth analysis of drugs acting on the autonomic nervous system, including adrenergic and cholinergic neurotransmitters. Sympathomimetic agents and adrenergic antagonists are explained with detailed mechanisms of action, classification, and structure-activity relationships (SAR). The book also explores cholinergic blocking agents, sedatives, hypnotics, and antipsychotics, alongside detailed classifications of anticonvulsants, general anesthetics, and analgesics, with an emphasis on their mechanisms, uses, and SAR.
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Dr. Sakshi Tomar
Dr. Sakshi is an Associate Professor in the Department of Pharmaceutical Chemistry at the Himalayan Institute of Pharmacy, Kala-Amb, in Sirmaur District, Himachal Pradesh. She holds a Ph.D. in Pharmaceutical Chemistry from Panjab University and an M.Pharm from Pune University. With over a decade of experience in teaching and research, Dr. Sakshi has made significant contributions to pharmaceutical research, particularly in the areas of crystal engineering and supramolecular chemistry, aimed at enhancing biopharmaceutical parameters. Her work has earned her several prestigious awards, including the UGC-RFSMS Fellowship, the Excellence in Academic and Research Award, and the Young Women Scientist Award at the Global Academic Excellence Award 2024 in Thailand
