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This book provides a comprehensive overview of the essential topics related to drug discovery and development, with a particular focus on the care, handling, and breeding techniques of laboratory animals, toxicity testing, and screening methods for pharmacological activity.
Designed for B.Pharm ,M.Pharm and Msc.Pharmacology students, as well as anyone involved in drug discovery and development, this book covers the following topics:
Care, handling, and breeding techniques of laboratory animals, along with alternative methods to animal studies
OECD guidelines and the determination of LD50, acute, sub-acute, and chronic toxicity studies
Organization of screening for pharmacological activity of new substances, with a particular emphasis on the evaluation of antipsychotics, antiepileptics, and antidepressants
Screening methods for anti-diabetic, antiulcer, CHF, and anti-hypertensive drugs, as well as screening methods for anti-inflammatory, analgesics, and antipyretic drugs
Throughout the book, the importance of preclinical studies in drug development and the role of screening methods in identifying potential drug candidates are emphasized. The ethical considerations related to animal experimentation are also discussed in detail.
This book is a valuable resource for anyone involved in drug discovery and development, providing a comprehensive overview of the essential topics related to pharmacology.
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Rao Muralidhar
Dr.Muralidhar Rao Akkaladevi has 25 years of teaching experience in Pharmacy and is currently the dean of studies at St.Mary's college of Pharmacy in Secunderabad. He has received numerous awards and fellowships throughout his career, including the Principal of the Year Award and the Rastriya Ratan Award.
He is a Fellow member of the APP, ISCA, and ICPHS and a life member of APTI, IPGA, IPS. He has served as a resource person for professional development programs and conferences, delivering lectures on a wide range of topics, including nano-technology advances in cancer treatment and emerging trends in pharmaceutical sciences.
He has authored 9 Pharmacy text books, Supervised Ph.D and M.Pharmacy Projects.
