The shortcomings of current treatment of AIDS range from undesirable
side effects, incomplete eradication of human immunodeficiency virus
(HIV) and an increase in the emergence of drug resistant viral strains.
Owing to these limitations, there has been a paradigm shift in the approach
of researchers as they now focus on the development of new drugs. More
convenient drugs will have enhanced activity, lesser or no side effects
and satisfactory delivery potential. Various approaches under investigation
use biomolecules and metals and/or synthetic compounds with the
potential to inhibit viruses or affect their binding sites on the host cells.
Techniques such as gene therapy or metal-based therapy emerge from this
concept and have so far contributed promising results for the control of
the HIV virus. This chapter explores current developments in gene and
metal-based therapies (enhanced by nanotechnology), with respect to the
design of effective drugs for the treatment of HIV infection.
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Dr. Dilpreet Singh, Prof. Pooja Chawla, Dr. Karan Razdan, Dr. Ravi Kant
Dr. Dilpreet Singh is working as an Associate Professor in ISF College of Pharmacy, Moga. He is a Gold Medalist in B.Pharmacy, University silver medalist in M.Pharmacy and Qualified Graduate Pharmacy Aptitude Test (GPAT) 3 times with Merit Position. He awarded Ph.D. and Post Doc from Guru Nanak Dev University, Amritsar. He also qualified CSIR-NET in December 2019 with Eligibility of Lectureship. His current research interest focus on Bioavailability Enhancement of drugs including Phytochemicals using lipid based technology, Design of Experiments/Quality by Design Paradigms, Systematic Optimization. He had now published 34 publications in International journal of repute. During his research work, he awarded with Homi Bhabha Felowship to collaborate his research work with King’s College London. He is life member of several professional bodies including AAPS, ACS, VERF-T, DDT-I, Boston. He qualified several MOOC courses, credit courses through Swayam UGC Platform and EDX courses through UGETY.
