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Subrat SaurabhAuthor of Kuch Woh Pal
When designing NCs for clinical applications, it should be clear that their systemic administration generates important modifications. In particular, the nonspecific interaction between NC surface and bloodstream proteins leads to the adsorption of opsonins on NCs, forming the so-called “protein corona.” These proteins substantially change the bare material properties determining the removal of NCs from circulation by the reticuloendothelial system (RES) in the spleen and liver. The most common RES-escaping approaches are to formulate NCs with neutral surface charge, by coating their surface with polyethylene glycol (PEG) and to use small size NCs. NCs with these features are called “stealth” NCs and can avoid the RES. Finally, NCs should be nontoxic, biodegradable, biocompatible, noninflammatory, and nonimmunogenic.
Dr Dilpreet Singh
Dr. Dilpreet Singh is working as an Associate Professor in ISF College of Pharmacy, Moga. He is a Gold Medalist in B.Pharmacy, University silver medalist in M.Pharmacy and Qualified Graduate Pharmacy Aptitude Test (GPAT) 3 times with Merit Position. He awarded Ph.D. and Post Doc from Guru Nanak Dev University, Amritsar. He also qualified CSIR-NET in December 2019 with Eligibility of Lectureship. His current research interest focus on Bioavailability Enhancement of drugs including Phytochemicals using lipid based technology, Design of Experiments/Quality by Design Paradigms, Systematic Optimization. He had now published 34 publications in International journal of repute. During his research work, he awarded with Homi Bhabha Felowship to collaborate his research work with King’s College London. He qualified CSIR NET (Life sciences), awarded with Lectureship. He is life member of several professional bodies including AAPS, ACS, VERF-T, DDT-I, Boston. He qualified several MOOC courses, credit courses through Swayam UGC Platform and EDX courses through UGETY.
